Pharmacological action: Generic accutane is active form of vitamin A,
can be synthesized in the body. Isotretinoin is not directly associated
with the nuclear retinoic acid receptors and their subclasses (alpha-,
beta-and gamma-receptors). It is rapidly converted into tretinoin
(all-trans retinoic acid) and other substance-ligand nuclear retinoic
acid receptor gene expression and gives cause changes in protein
synthesis (depending on the tissue - either induction or inhibition).